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Department of Chemistry and Chemical Biology

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Faculty Detail


Ganem, Bruce

Franz and Elisabeth Roessler Professor and J. Thomas Clark Professor of Entrepreneurship and Personal Enterprise

email:
phone: 607/255-7360
room: Baker Laboratory, Room 332

Department Appointments

  • Chemistry and Chemical Biology (CHEM)
  • Ganem, Bruce

Graduate Fields

  • Chemistry and Chemical Biology

Overview

A synthetic organic chemist by training, Dr. Ganem has broad scientific research interests ranging from organic and analytical chemistry to biochemistry.   

Research

•  Synthetic organic chemistry, natural products synthesis

 •  New synthetic methodology, multicomponent reactions

•  Drug discovery and development

• Biochemistry, molecular medicine. 

Selected Publications

C. A. Simoneau, A. M. Strohl, B. Ganem, “A Novel, One-Pot Synthesis of Polysubstituted Indoles from Aliphatic Nitro Compounds,” Tetrahedron Lett. 48, 1809 (2007).

 Ganem, B. “Strategies for Innovation in Multicomponent Reaction Design,” Acc. Chem. Res. 42, 463 (2009).

 J. M. Oaksmith, B. Ganem, “Synthesis of a COMC-Estradiol Conjugate for Targeted, Tissue-selective Cancer Chemotherapy.” Tetrahedron Lett. 50, 3497 (2009).

 L. Fan, R. W. Lewis, G. P. Hess, B. Ganem, “A New Synthesis of Caged GABA Compounds for Studying GABAA Receptors,” Bioorg. Med. Chem. Lett. 19, 3932 (2009).

 H. V. Le, L. Fan, B. Ganem, “A Practical and Inexpensive ‘Convertible’ Isonitrile for Use in Multicomponent Reactions,” Tetrahedron Lett. 52, 2209 (2011).

 H. V. Le, B. Ganem, “Mild Oxidation of Tosylmethylisocyanide to Tosylmethylisocyanate: Utility in Synthetic and Medicinal Chemistry,” Tetrahedron Lett. 55, 2003 (2014).